In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 10488-69-4, name is Ethyl 4-chloro-3-hydroxybutanoate, the common compound, a new synthetic route is introduced below. Safety of Ethyl 4-chloro-3-hydroxybutanoate
(1) Ethyl S-4-chloro-3-hydroxybutyrate was stirred with 60percent by weight of DMSO and 1-fold by weight of sodium azide at 60 ° C for 5 hours, The solvent is DMF, n-propanol, isopropanol, n-butanol, tert-butanol, toluene or cyclopentanol and so on to get the intermediate I, and the reaction is complete, stop the reaction, direct concentration to remove the solvent,
The synthetic route of 10488-69-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Chongqing East Ze Pharmaceutical Technology Development Co., Ltd.; Yuan, Huajie; Dai, Liping; Xie, Lingling; Ye, Lei; (24 pag.)CN105330581; (2016); A;,
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