Synthetic Route of 101597-25-5 ,Some common heterocyclic compound, 101597-25-5, molecular formula is C17H16O3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Step 7 The product of Step 6 (4.8 g), was dissolved in dichloromethane (150 mL) in a 3-necked 100 mL round bottom flask, followed by addition of p-toluenesulfonic acid monohydrate (0.4 g). 1,1-Bis(4-methoxyphenyl)-2-propyn-1-ol (3.8 g) was added to the reaction mixture slowly. The mixture was stirred at room temperature. After one hour, more 1,1-bis(4-methoxyphenyl)-2-propyn-1-ol, (0.4 g) was added to the reaction mixture. After stirring for two hours, the reaction was worked up with the addition of saturated aqueous NaHCO3 (100 mL). The resulting organic layer was collected and dried over anhydrous MgSO4. The organic layer was concentrated under vacuum to provide product (8.7 g).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,101597-25-5, its application will become more common.
Reference:
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Alcohols – Chemistry LibreTexts