Related Products of 627-18-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 627-18-9, name is 3-Bromopropan-1-ol, molecular formula is C3H7BrO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
At room temperature,In a 500 mL round bottom flask was added dichloromethane (200 mL) and p-toluenesulfonic acid (1.72 g,10 mmol), stirred and dissolved.Then 3-bromo-1-propanol (13.90 g, 100 mmol) and 2,3-dihydropyran (12.60 g, 150 mmol) were added sequentially, and the reaction was stirred for 12 h.After the reaction was completed, it was quenched with water and the organic phase was separated.The aqueous phase was extracted with dichloromethane (3×100 mL). The organic phase was washed with aq. aq.Finally purified by silica gel column chromatography (petroleum ether / ethyl acetate 30:1).Obtained yellow-green oily liquid 1-tetrahydropyranyloxy-3-bromopropane 2(19.68 g, yield 88%).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 627-18-9, 3-Bromopropan-1-ol.
Reference:
Patent; China Agricultural University; Zhong Jiangchun; Sun Xiao; Bian Qinghua; Wang Min; Zhou Yun; Yuan Gucheng; (7 pag.)CN109970534; (2019); A;,
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