Adding a certain compound to certain chemical reactions, such as: 10488-69-4, Ethyl 4-chloro-3-hydroxybutanoate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 10488-69-4, blongs to alcohols-buliding-blocks compound. Recommanded Product: Ethyl 4-chloro-3-hydroxybutanoate
S(-)-4-chloro-3-hydroxybutyric acid ethyl ester (100g) andL-2-Aminobutyramide is the starting material (61.3g),With chloroform as solvent,Add acid agent potassium carbonate (81.3g),While stirring at reflux, the reaction was incubated for 4 hours.After confirming that the reaction of raw materials is completed, the reaction solution is washed twice with 150 mL of dichloromethane, and the organic phase is dried.It is reduced to no fractions and purified by column to give product intermediate I, namely (S)-2-((S)-4-hydroxy-2-oxopyrrolidin-1-yl)butyrylAmine, 96.3 g, purity 98.4percent, yield 86.3percent.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,10488-69-4, its application will become more common.
Reference:
Patent; Emeishan Hongsheng Pharmaceutical Co., Ltd.; Lu Chengxian; Tian Jianhong; Tian Yangyang; Che Shangze; Tian Jinyuan; (10 pag.)CN107513032; (2017); A;,
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