Sources of common compounds: Dimethyl 3-hydroxypentanedioate

Statistics shows that 7250-55-7 is playing an increasingly important role. we look forward to future research findings about Dimethyl 3-hydroxypentanedioate.

Application of 7250-55-7, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.7250-55-7, name is Dimethyl 3-hydroxypentanedioate, molecular formula is C7H12O5, molecular weight is 176.17, as common compound, the synthetic route is as follows.

Example 1 (Synthesis of dimethyl 3-benzyloxycarbonyloxyglutarate) In 10 ml of 1,2-dichloromethane was dissolved 1.01 g (5.78 mmol) of dimethyl 3-hydroxyglutarate, 847 mg (6.93 mmol) of 4,4-dimethylaminopyridine and 990 mul (6.93 mmol) of benzyloxycarbonyl chloride were added to the solution at room temperature, and the mixture was reacted at 0C for 30 minutes, and at room temperature for 1 hour under stirring. After completion of the reaction, the obtained reaction mixture was concentrated under reduced pressure, and the organic layer was extracted by adding 20 ml of ethyl acetate and 10 ml of water. The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to obtain an oily substance.

Statistics shows that 7250-55-7 is playing an increasingly important role. we look forward to future research findings about Dimethyl 3-hydroxypentanedioate.

Reference:
Patent; Ube Industries, Ltd.; EP1500642; (2005); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts