Adding a certain compound to certain chemical reactions, such as: 55414-72-7, (2-Amino-5-methoxyphenyl)methanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 55414-72-7, blongs to alcohols-buliding-blocks compound. Recommanded Product: 55414-72-7
In a 50 mL round bottom flask, 2 mmol of 2-amino-5-methoxybenzyl alcohol (Formula (1-3)), 2 mmol of benzaldehyde (Formula (2-1)), 0.2 mmol of ABNO, 0.6 was added. The KOH of mmol and the toluene of 4mL replace the air in the bottle with oxygen, seal the bottle mouth with a rubber stopper and insert an oxygen balloon.The reaction flask was placed in a pre-heated oil bath and heated to 80C for 5 hours.The solvent was distilled off under reduced pressure and then subjected to column chromatography. The mixture of ethyl acetate/petroleum ether having a volume ratio of 1:50 was used as an eluent to collect the eluent containing the target compound, and the solvent was distilled off to obtain the product 6- Methoxy-2-phenyl-4H-3,1-benzoxazine with isolated yield of 94%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,55414-72-7, its application will become more common.
Reference:
Patent; Zhejiang University of Technology; Shen Zhenlu; Li Meichao; Ma Jiaqi; Hu Xinquan; Hu Baoxiang; (13 pag.)CN106831632; (2017); A;,
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