As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 112-47-0, name is 1,10-Decanediol, molecular formula is C10H22O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Recommanded Product: 112-47-0
EXAMPLE 3 10-Bromo-1-decanol A solution of 1,10-dihydroxydecane (80 g) in 47% hydrobromic acid (650 ml) was stirred at 80C whilst being continuously extracted with petroleum ether (boiling range 80-100), for 24 hours. The organic extracts were neutralised with solid potassium carbonate, filtered, and the filtrates evaporated to dryness. The resultant dark oil was fractionally distilled (Vigreaux apparatus) to give a colourless oil, boiling point 102-104 (0.01 mm Hg). Part of this oil (52 g) was purified by preparative HPLC (silica; eluents:diethyl ether/hexane 1:1) to remove a significant 1,10-dibromodecane impurity, finally yielding the title compound as a colourless oil.
With the rapid development of chemical substances, we look forward to future research findings about 112-47-0.
Reference:
Patent; Lilly Industries Limited; EP190042; (1991); B1;,
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