Related Products of 627-27-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 627-27-0, name is But-3-en-1-ol, molecular formula is C4H8O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
But-3-en-1-yl methanesulfonate 8 was prepared from 3-buten-1-ol using the protocol described byD. Pei et al.:2 methanesulfonyl chloride (1.10 equiv, 110 mmol, 8.51 mL) was added dropwise to asolution of 3-buten-1-ol (1.00 equiv, 100 mmol, 7.21 g) and triethylamine (1.10 equiv, 110 mmol,15.3 mL) in CH2Cl2 (0.20 L) at 0 C. The mixture became cloudy. After 5 min of stirring, the coldbath was removed and stirring was continued for 1 h. The reaction mixture was then washed withsaturated NaHCO3 aqueous solution (0.10 L) and H2O (0.10 L). The organic layer was dried overMgSO4, filtered and concentrated to afford mesylate 8 (14.3 g, 95.2 mmol, 95%) as a colourless oilthat was used as such, without purification.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 627-27-0, But-3-en-1-ol.
Reference:
Article; Wolan, Andrzej; Kowalska-Six, Justyna A.; Rajerison, Holisoa; Cesario, Michele; Cordier, Marie; Six, Yvan; Tetrahedron; vol. 74; 38; (2018); p. 5248 – 5257;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts