Synthetic Route of 929-06-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 929-06-6, name is 2-(2-Aminoethoxy)ethanol, molecular formula is C4H11NO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
To a 500mL three-necked flask were added compound BG04 3.7g (1. 0eq), (Boc)2O 15.5g (2.0 eq), a mixed solution of methanol:triethylamine (9:1) 200ml, stirred and warmed to reflux, and reacted for 1h. After the completion of the reaction under the monitor of TLC, methanol triethylamine was evaporated off, and dissolved in water. Dichloromethane was extracted for 3 times. The organic layers were combined and washed once with water, dried over anhydrous sodium sulfate, and concentrated to give 4.8g BG05 as an oil.
According to the analysis of related databases, 929-06-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Bright Gene Bio-Medical Technology Co., Ltd.; YUAN, Jiandong; HUANG, Yangqing; SONG, Yunsong; YUAN, Fang; (69 pag.)EP3321279; (2018); A1;,
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