The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 111-46-6, name is 2,2′-Oxybis(ethan-1-ol). This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)
In steel esterification reactor with the volume of 15 1 equipped with a heating element and a stirring device, 3550 g of benzoic acid, 1500 g of diethylene glycol are charged, 13 g of titanium (IV) isopropoxide are added. Before the heating treatment, xylene in the amount of 2500 g is added to separator. The reaction is conducted at the constant feed of xylene into the reaction mass by the circulating pump from the separator with the rate of 3 1/hour. The reaction mass is heated to the temperature 200C, in an hour after the beginning of the heating the temperature is raised to 220C, in two hours after the beginning of the heating the temperature is raised to 240C. In 3 hours after the beginning of the heating the pressure in. reactor is reduced to 15 kPa, in 30 min more the pressure in reactor is reduced to 5 kPa. In 4 hours after the beginning of the heating the reaction mass is cooled. From the esterification reactor 4400 g of reaction mass comprising 0.5% by weight of benzoic acid, 0.3 % by weight of diethylene glycol benzoate and 99.0% by weight of diethylene glycol dibenzoate are discharged. From the separator an aqueous phase comprising 785 g of water, 8 g of benzoic acid, as well as organic phase comprising 1720 g of xylene, 365 g of benzoic acid, is discharged.
With the rapid development of chemical substances, we look forward to future research findings about 111-46-6.
Reference:
Patent; PUBLIC JOINT STOCK COMPANY “SIBUR HOLDING”; NOSIKOV, Aleksei Aleksandrovich; BABIN, Ivan Anatolievich; POPOVTSEV, Egor Evgenievich; IGASHEVA, Varvara Petrovna; (28 pag.)WO2019/59801; (2019); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts