Electric Literature of 869725-53-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 869725-53-1, name is 2-Bromo-5-(trifluoromethyl)benzyl Alcohol, molecular formula is C8H6BrF3O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Step 3: 2-Bromo-5-trifluoromethyl-benzaldehyde[00420] 2-Bromo-5-(trifluoromethyl)benzyl alcohol (2.216g, 8.69mmol) and N- methylmorpholine-N-oxide (2.051g, 17.38mmol) were combined in CH2Cl2 (44mL) and MeCN (2.2mL). Tetrapropylammonium perruthenate (0.31 Ig, 0.87mmol) was added, and the reaction was stirred for 20 minutes at room temperature. Once no starting material was seen by analytical tic, the mixture was concentrated, and the residue was purified by silica gel chromatography to give the title compound.
According to the analysis of related databases, 869725-53-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; AMIRA PHARMACEUTICALS, INC.; HUTCHINSON, John, Howard; SEIDERS, Thomas, Jon; ARRUDA, Jeannie, M.; ROPPE, Jeffrey, Roger; WO2010/42652; (2010); A2;,
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