As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 55362-80-6, name is 9-Bromononan-1-ol, molecular formula is C9H19BrO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Recommanded Product: 55362-80-6
A mixture of 9-bromo-1-nonanol (1.1 kg) N, N-dimethylformamide (2.86 L), Imidazole (363 g) Was added to 10 L of the reaction flask, To the ice bath was added dimethyl tert-butylchlorosilane (772 g) Temperature below 20 C, reaction for 1 hour, Add water (5 L), Toluene (1 L), Stir, Dispensing, The aqueous phase was extracted with toluene (1 L) Mixed organic phase, The organic phase was washed with water (1 L) Dried over anhydrous sodium sulfate, At 80 C, Get 1.56 kg product, Directly for the next step reaction
With the rapid development of chemical substances, we look forward to future research findings about 55362-80-6.
Reference:
Patent; Tianjin Pharmaceutical Innovation Co., Ltd.; LIU, WENJUAN; MO, LAN; (14 pag.)CN103965280; (2016); B;,
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