Synthetic Route of 14631-46-0 ,Some common heterocyclic compound, 14631-46-0, molecular formula is C9H11NO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
The intermediate 8-hydroxy-5,6,7,8-tetrahydroquinoline was prepared according to the procedure described in Bridger et. al. PCT International application PCT/CA00/00321. For the purposes of illustration, the synthesis of (R)-(-)-8-amino-5,6,7,8-tetrahydroquinoline is described.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,14631-46-0, its application will become more common.
Reference:
Patent; McEachern, Ernest J.; Bridger, Gary J.; Skupinska, Krystyna A.; Skerlj, Renato T.; US2003/114679; (2003); A1;,
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