Application of 13674-16-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 13674-16-3, name is Methyl 2-hydroxy-3-phenylpropanoate. This compound has unique chemical properties. The synthetic route is as follows.
[0177] Example 18: Synthesis of 2-(4 -AMINO-BIPHENYL-4-YLOXY)-3-PHENYL-PROPIONIC acid methyl ester.; [0178] Step 1: 2- (4 -NITRO-BIPHENYL-4-YLOXY)-3-PHENYL-PROPIONIC acid methyl ester. A mixture OF 4 -HYDROXY-4-NITRO-BIPHENYL (4.12 g, 19.1 mmol), prepared in step 2 of Example 16, 2-hydroxy-3-phenyl-propionic acid methyl ester (3.35 g, 18. 5 mmol) and triphenylphosphine (4.12 g, 19.1 MMOL.) in diethyl ether was cooled under nitrogen to 0C. Diisopropyl azodicarboxylate (6.09 mL, 30.96 mmol) was then added and the reaction allowed to come to room temperature and then stirred overnight at room temperature. The reaction was concentrated under reduced pressure. Purification of the residue on silica gel using 15% ethyl acetate hexanes as the eluent gave 2- (4 -NITRO-BIPHENYL-4-YLOXY)-3-PHENYL-PROPIONIC acid methyl ester.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 13674-16-3, Methyl 2-hydroxy-3-phenylpropanoate.
Reference:
Patent; WYETH; WO2005/30702; (2005); A1;,
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