In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3068-00-6, name is 1,2,4-Butanetriol, the common compound, a new synthetic route is introduced below. Product Details of 3068-00-6
A 100 mL RBF was charged with dilinolenyl ketone (Compound 7) (4.2 g, 8.2 mmol), 1,2,4-butanetriol (3.4 g, 32 mmol), PPTS (200 mg, 0.8 mmol) and a stir bar. The flask was flushed with nitrogen and anhydrous toluene (60 mL) added. The reaction vessel was fitted with a Dean Stark tube and condenser and brought to reflux and the reaction was left overnight. After cooling to room temperature, the reaction mixture diluted with toluene (50 mL), and washed with 5% aq. Na2C03 (2 chi 50 mL), water (50 mL), dried (MgS04) and purified by chromatography to yield 3.0 g (4.9 mmol, 59%) of the ketal.
The synthetic route of 3068-00-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; PROTIVA BIOTHERAPEUTICS, INC; HEYES, James; WOOD, Mark; MARTIN, Alan; WO2011/141704; (2011); A1;,
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