Reference of 110-73-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 110-73-6, name is 2-(Ethylamino)ethanol, molecular formula is C4H11NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: To a solution of 2-(chloromethyl)-4-(cyclohexylmethoxy)-1Hbenzo[d]imidazole 7 (0.72 mmol) in DMF (5 mL), K2CO3(0.79 mmol) and appropriate amine 8 or 9 or 10 (0.79 mmol) wereadded. The resulting solution was stirred at 60 C for 3 h. Themixture was cooled, diluted with water, and then extracted withEtOAc. The combined organic extracts were washed with water,brine solution, dried over anhydrous Na2SO4 and then concentratedunder reduced pressure. The crude mixture was subjected to flashsilica gel (230-400 mesh) column chromatography (eluting with0e2% MeOH in dichloromethane) to afford the title compounds 5.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 110-73-6, 2-(Ethylamino)ethanol.
Reference:
Article; Boggu, Pulla Reddy; Kim, Youngsoo; Jung, Sang-Hun; European Journal of Medicinal Chemistry; vol. 181; (2019);,
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