Synthetic Route of 16545-68-9, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 16545-68-9, Name is Cyclopropanol, SMILES is OC1CC1, belongs to alcohols-buliding-blocks compound. In a article, author is Razmimanesh, Fariba, introduce new discover of the category.
An investigation into Sunitinib malate nanoparticle production by US- RESOLV method: Effect of type of polymer on dissolution rate and particle size distribution
The present study practiced ultrasonic-assisted rapid expansion of a supercritical CO2 solution into a liquid solvent (US-RESOLV) process for the synthesis of nanoparticles (NPs) of Sunitinib malate for the first time. Hydrophilic polymers including hydroxypropyl methylcellulose (HPMC), poly (vinyl alcohol) (PVA), chitosan (CHI) and polyethylene glycol (PEG) were utilized for modifying the size distribution and increasing the dissolution rate of the Sunitinib malate NPs. Also, we determined the impact of pressure, nozzle diameter as well as temperature on morphology, size distribution and dissolution rate of produced particles. In order to accomplish the objectives of the present study, PEG was the best polymer for controlling the particle size distribution and HPMC served as the best polymeric stabilizer for increasing the dissolution rate of the drug particles. The synthesized particles were much smaller (< 600 nm) in comparison to the unprocessed particles of Sunitinib malate. The combined effects of the smaller sizes of the particles, ultrasonication and the presence of polymers could enhance dissolution rate of the Sunitinib malate in the aqueous media. Synthetic Route of 16545-68-9, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 16545-68-9 is helpful to your research.
Reference:
Alcohol – Wikipedia,
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