Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Safety of 2-(4-Methoxyphenyl)ethanol, 702-23-8, Name is 2-(4-Methoxyphenyl)ethanol, SMILES is COC1=CC=C(CCO)C=C1, belongs to alcohols-buliding-blocks compound. In a document, author is Porey, Arka, introduce the new discover.
Hydrogen-Bonding Assisted Catalytic Kinetic Resolution of Acyclic beta-Hydroxy Amides
Enantioenriched acyclic alpha-substituted beta-hydroxy amides are valuable compounds in chemical, material and medicinal sciences, but their enantioselective synthesis remains challenging. A catalytic kinetic resolution (KR) of such amides with selectivity factor(s) up to >200 is developed via enantioselective acylation of primary alcohol with N-heterocyclic carbene. An enhanced selectivity for the catalytic KR process is realized using cyclic tertiary amine as base additive. Diastereomeric transition state models for the process are proposed to rationalize the origin of enantioselectivity.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 702-23-8. Safety of 2-(4-Methoxyphenyl)ethanol.
Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts