The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Quality Control of 2-Amino-2-ethylpropane-1,3-diol, 115-70-8, Name is 2-Amino-2-ethylpropane-1,3-diol, SMILES is OCC(CC)(N)CO, in an article , author is Caliandro, Rosanna, once mentioned of 115-70-8.
The structural and functional characterization of Malus domestica double bond reductase MdDBR provides insights towards the identification of its substrates
In this study we describe the crystal structures of the apoform, the binary and the ternary complexes of a double bond reductase from Malus domestica L. (MdDBR) and explore a range of potential substrates. The overall fold of MdDBR is similar to that of the medium chain reductase/dehydrogenase/zinc-dependent alcohol dehydrogenase-like family. Structural comparison of MdDBR with Arabidopsis thaliana DBR (AtDBR), Nicotiana tabacum DBR (NtDBR) and Rubus idaeus DBR (RiDBR) allowed the identification of key amino acids involved in cofactor and ligands binding and shed light on how these residues may guide the orientation of the substrates. The enzyme kinetic for the substrate trans-4-phenylbuten-2-one has been analyzed, and MdDBR activity towards a variety of substrates was tested. This enzyme has been reported to be involved in the phenylpropanoid pathway where it would catalyze the NADPH-dependent reduction of the alpha, beta-unsaturated double bond of carbonyl metabolites. Our study provides new data towards the identification of MdDBR natural substrate and the biosynthetic pathway where it belongs. Furthermore, the originally proposed involvement in dihydrochalcone biosynthesis in apple must be questioned. (C) 2020 Elsevier B.V. All rights reserved.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 115-70-8, you can contact me at any time and look forward to more communication. Quality Control of 2-Amino-2-ethylpropane-1,3-diol.
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