In an article, author is Liu, Bingxian, once mentioned the application of 42142-52-9, Recommanded Product: 3-(Methylamino)-1-phenylpropan-1-ol, Name is 3-(Methylamino)-1-phenylpropan-1-ol, molecular formula is C10H15NO, molecular weight is 165.2322, MDL number is MFCD00674078, category is alcohols-buliding-blocks. Now introduce a scientific discovery about this category.
Rhodium-Catalyzed Enantioselective Synthesis of beta-Amino Alcohols via Desymmetrization of gem-Dimethyl Groups
Desymmetrization of gem-dimethyl groups en route to the rhodium(III)-catalyzed enantioselective sp(3) C-H amidation is reported. Synthetically important beta-amino alcohol derivatives were accessed in moderate to good yields and high enantioselectivity. The high enantioselectivity is enabled by an appropriate oxime directing group, sterically biased gem-groups in the C-H substrate, and high reactivity of the amidating reagent.
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Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts