Related Products of 67853-03-6, Adding some certain compound to certain chemical reactions, such as: 67853-03-6, name is Methyl 3-(hydroxymethyl)benzoate,molecular formula is C9H10O3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 67853-03-6.
To a cooled (0 C) solution of 3 (4.6 g, 27.5 mmol) in anhydrous DCM (75 ml) was slowly added PBr3 solution (11.2 g, 41.3 mmol) under nitrogen atmosphere. The reaction mixture was allowed to gradually reached room temperature and stirred for 2 hours. The reaction vessel was cooled in ice bath and the contents were quenched by slowly adding saturated NaHCO3 solution till slightly basic pH (7 – 8). The organic layer was washed with brine, water, dried with sodium sulphate and evaporated to yield 4 as white crystals (4.4 g, 69%). The product was used in the next step without further purification.
According to the analysis of related databases, 67853-03-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Veron, Jean-Baptiste; Joshi, Advait; Wallinder, Charlotta; Larhed, Mats; Odell, Luke R.; Bioorganic and Medicinal Chemistry Letters; vol. 24; 2; (2014); p. 476 – 479;,
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