In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 15484-46-5, name is Methyl 2-(hydroxymethyl)acrylate, the common compound, a new synthetic route is introduced below. SDS of cas: 15484-46-5
Example 54; Acetic anhydride (87 g) as a derivatizing agent was added dropwise over a period of 1 hour to 371 g of the reaction mixture obtained in Example 53, and the mixture was stirred for 2 hours at 50C. The amount of methyl alpha-(hydroxyethyl) acrylate in 458 g of this reaction mixture was 2 g. The reaction mixture was then washed with water to remove the catalyst, following which purification was carried out by distillation using a distillation apparatus (theoretical number of plates, 13) and under reduced pressure (operating pressure, 2 kPa). The amount of reaction mixture prior to distillation was 450 g, and included 256 g of methyl alpha-(allyloxymethyl) acrylate, 1 g of methyl alpha-(hydroxymethyl) acrylate and 30 g of methyl alpha-(acetoxymethyl) acrylate. Following distillation, 192 g of product containing 99.3 wt% of methyl alpha-(allyloxymethyl) acrylate and 0.2 wt% of methyl alpha-(hydroxymethyl) acrylate was obtained.
The synthetic route of 15484-46-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Nippon Shokubai Co., Ltd.; EP2415751; (2012); A1;,
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