Reference of 37585-25-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 37585-25-4, name is (2-Amino-5-chlorophenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
Oxidation of (2-amino-phenyl)-methanols (3) to 2-amino-benzaldehydes (4) -General procedure; [0082] (2-Amino-phenyl)-methanol (12 mmol) in dry diethyl ether (25 ml_) is added dropwise to a mixture of manganese dioxide (48 mmol) in dry diethyl ether (25 ml_) and the mixture is stirred at rt overnight. The solution is filtered through a celite and the solvent is removed at reduced pressure. The crude product is used in the next step without further purification.; 2-Amino-5-crtloro-benzaldehyde; Yield 99%; 1H NMR (CDCI3): 6.14 (br s, 2H); 6.61 (d, 9 Hz, 1 H); 7.25 (dd, 9 and 2 Hz, 1 H); 7.44 (d, 2 Hz, 1 H) and 9.80 (s, 1 H).
According to the analysis of related databases, 37585-25-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERZ PHARMA GMBH & CO KGAA; HENRICH, Markus; BAUER, Angela; NAGAL, Jens; SLADEK, Meik; PARSONS, Christopher, Graham, Raphael; DANYSZ, Wojciech; KRAUSS, Valerjans; ROZHKOVS, Jevgenijs; STARCHENKOVS, Igors; TRIFANOVA, Dina; WO2010/37533; (2010); A1;,
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