Related Products of 61487-25-0, Adding some certain compound to certain chemical reactions, such as: 61487-25-0, name is (2-Amino-3-chlorophenyl)methanol,molecular formula is C7H8ClNO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 61487-25-0.
EXAMPLE 82 Preparation of 2-chloro-6-methoxymethylaniline A solution of 4.00 g (25.4 mmol) of 2-amino-3-chlorobenzyl alcohol in 30 ml of dry THF was cooled to -78 C., treated with 16.7 ml (26.7 mmol) of 1.60M n-butyllithium in hexane, warmed to 0-5 C., treated with 3.61 g (25.4 mmol) of methyl iodide and heated at reflux for 5.5 hours. The solvent was removed by evaporation at reduced pressure. The residue was partitioned between 175 ml of ether and water, and the organic phase was separated and dried (MgSO4). The solvent was removed by evaporation at reduced pressure, and the residue was purified by HPLC eluding with ETOAc (5:95, v/v) to afford 1.1 g of the desired product as a pale brown oil. IR and 1 H NMR spectra were in agreement with the assigned structure. Analysis: Calculated for C8 H10 ClNO: C, 56.00; H, 5.87; N, 8.16; Found: C, 56.25; H, 5.98; N, 8.28.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 61487-25-0, (2-Amino-3-chlorophenyl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; The Dow Chemical Company; US4755212; (1988); A;,
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