Related Products of 64372-62-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.64372-62-9, name is 2-Chloro-5-(trifluoromethyl)benzyl alcohol, molecular formula is C8H6ClF3O, molecular weight is 210.58, as common compound, the synthetic route is as follows.
General procedure: To a mixture of 12 (66 mg, 0.366 mmol) and the alcohol(0.549 mmol) in n-octane (3 mL) was added H-mont (260 mg), andthen the mixture was stirred at room temperature until the TLCindicated the consumption of the starting material. The reactionmixture was filtered to remove H-mont, and the filtrate wasevaporated under reduced pressure. The residue was purified byflash chromatography (petroleum ether/ethyl acetate 300:1 to200:1) to give the product. Following the procedure, 16f,g wereprepared.
Statistics shows that 64372-62-9 is playing an increasingly important role. we look forward to future research findings about 2-Chloro-5-(trifluoromethyl)benzyl alcohol.
Reference:
Article; Chen, Dongyin; Xu, Chang; Deng, Jie; Jiang, Chunhuan; Wen, Xiaoan; Kong, Lingyi; Zhang, Ji; Sun, Hongbin; Tetrahedron; vol. 70; 11; (2014); p. 1975 – 1983;,
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