Sources of common compounds: (2,6-Dimethylphenyl)methanol

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 62285-58-9, name is (2,6-Dimethylphenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of (2,6-Dimethylphenyl)methanol

A solution of 2,6-Dimethylbenzyl alcohol (5.25 g, 38.6 mmol) and diisopropyl azodicarboxylate (DIAD, 8.49 g, 42 mmol) in THF (30 ml) and DMF (13 ml) was added drop wise to a solution of Ethyl 3-hydroxyphenylacetate (Step A, 6.66 g, 37 mmol) and triphenylphosphine (1 Ig, 42 mmol) in THF (100 ml). The reaction mixture was stirred at room temperature for 4 hours, diluted with ether and washed with water. The organic layer was dried over Na2SO4, filtered, concentrated, and purified by flash EPO chromatography on a silica gel column (hex: ethyl acetate 1:1) to give the title compound.1H NMR (270 MHz5 CDCl3): 1.2 (t, 3H); 2.4 (s, 6H); 3.5 (s, 2H); 4.1 (q, 2H); 5.1 (s, 2H); 6.9 (m, 2H); 7.15-7.35 (m, 5H).

With the rapid development of chemical substances, we look forward to future research findings about 62285-58-9.

Reference:
Patent; WELLSTAT THERAPEUTICS CORPORATION; WO2006/127133; (2006); A2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts