Extracurricular laboratory: Synthetic route of 44565-27-7

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 44565-27-7, 4-Amino-2-methylbutan-1-ol.

Synthetic Route of 44565-27-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 44565-27-7, name is 4-Amino-2-methylbutan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

Compound 7b (90 mg, 0.26 mmol) and 4-amino-2-methyl-butan-1-ol (40 mg, 0.26 mmol) were refluxed overnight in BuOH (2 mL). The resulting solution was poured into saturated NH4Cl solution, and extractedwith EtOAc. The organic layer was washed with saturated NaCl, and then dried over Na2SO4, evaporated under reduce pressure. The residue was purified by a silica gel column chromatography (CHCl3:MeOH=95:5) to give 3b as white powder (73 mg, 68 % yield).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 44565-27-7, 4-Amino-2-methylbutan-1-ol.

Reference:
Article; Hayashi, Ken-Ichiro; Kusaka, Naoyuki; Ando, Kazuki; Mitsui, Taichi; Aoyama, Takashi; Nozaki, Hiroshi; Bioorganic and Medicinal Chemistry Letters; vol. 22; 17; (2012); p. 5663 – 5667;,
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