Analyzing the synthesis route of 3-(Benzylamino)-1-propanol

With the rapid development of chemical substances, we look forward to future research findings about 4720-29-0.

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 4720-29-0, name is 3-(Benzylamino)-1-propanol. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C10H15NO

(a) A solution of 7 g of 3-N-benzylamino-propanol in 40 ml of dimethylformamide is reacted analogously to the process described in Example (1a) with 1.9 g of a sodium hydride suspension (55% strength in paraffin oil), and then with 5.5 g of 6-chloro-nicotinic acid amide. The crude 6-(3-N-benzylamino-propyloxy)-nicotinic acid amide thus obtainable is reacted with 4.9 g of 1,2-epoxy-3-(2-methyl-phenoxy)propane; this gives 1-{N-benzyl-N-[3-(5-carbamoyl-2-pyridyloxy)-propyl]-amino}-3-(2-methyl-phenyloxy)-2-propanol, which is processed further without purification.

With the rapid development of chemical substances, we look forward to future research findings about 4720-29-0.

Reference:
Patent; Ciba-Geigy Corporation; US4027027; (1977); A;,
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