Application of 627-18-9, Adding some certain compound to certain chemical reactions, such as: 627-18-9, name is 3-Bromopropan-1-ol,molecular formula is C3H7BrO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 627-18-9.
Bromopropanol (1.38g, 0.01mol) and sodium azide (0.975g, 0.015mol) were dissolved in N,N-dimethylformamide (DMF) and reacted under nitrogen for 90 h at 12 C. . After the reaction is completed, the solution is cooled to room temperature, diluted with a certain amount of water, and the aqueous layer is washed with a large amount of diethyl ether. The ether solution is collected and dried overnight with anhydrous NaS04. The crude product after filtration is purified by column chromatography. The residual DMF organic solvent is removed, and the developing solvent is ethyl acetate: petroleum ether = 1:5, and the obtained colorless liquid is the product azidopropanol.The yield was 0.873 g and the yield was 86.4%. Azido hexanol (0.69 g, 89.2%) and azido undecanol (0.98 g, 91.7%) were prepared by the same procedure.
According to the analysis of related databases, 627-18-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shanghai Jiao Tong University; Zhu Xinyuan; Zhang Jun; Fan Wenbin; Zhang Chuan; Xue Feng; Tong Gangsheng; (15 pag.)CN109912528; (2019); A;,
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