As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 756520-66-8, name is 1-(2,6-Dichloro-3-fluorophenyl)ethanol, molecular formula is C8H7Cl2FO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Recommanded Product: 756520-66-8
Compound 1 – (2, 6 – dichloro -3 – fluoro phenyl) ethanol (4.6 g, 22 mmol), P2 O5 (17.5 G, 0 . 12 muM, 5.6 eq.) and DCM (200 ml) of the reaction suspension at room temperature 16 hours, filtering, filtering solid, solid for DCM (200 ml) washing, Na filtrate saturation2 CO3 Aqueous solution (100 ml x 2) washing, separating, the obtained organic phase with anhydrous Na2 SO4Drying, concentrated under reduced pressure, the concentrate produced in the process of filtering the white solid, the obtained oily material vacuum drying to obtain the crude product of the title compound (3.5 g, 83%), without further purification, is directly used for the next step reaction
With the rapid development of chemical substances, we look forward to future research findings about 756520-66-8.
Reference:
Patent; (88 pag.)CN104119331; (2018); B;,
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