Synthetic Route of 6351-10-6 , The common heterocyclic compound, 6351-10-6, name is 2,3-Dihydro-1H-inden-1-ol, molecular formula is C9H10O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: The acetates were synthesized by classical chemical acetylations via the corresponding racemic alcohol (1 equiv), using 1.5 equiv of anhydride acetic, 1.2 equiv of Et3N, and a catalytic amount of 4-dimethylaminopyridine (0.1 equiv) in 4 ml of ether. The acetates were obtained pure after standard work-up. The 1H NMR spectra of these products were in good agreement with the literature.
The synthetic route of 6351-10-6 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Merabet-Khelassi, Mounia; Houiene, Zahia; Aribi-Zouioueche, Louisa; Riant, Olivier; Tetrahedron Asymmetry; vol. 23; 11-12; (2012); p. 828 – 833;,
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