Application of 5333-42-6 , The common heterocyclic compound, 5333-42-6, name is 2-octyldodecan-1-ol, molecular formula is C20H42O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General synthesis of beta-glycosides (amounts based on branched C24 disaccharide glycosides) A solution of 3.4 T beta-peracetate and.2.3 g 2-decyl-tetradecanol in 50 mL anhydrous dichloromethane was treated with 600 muL borontrifluoride dimethyletherate and kept at room temperature for about 5-48 h. The mixture was washed with aqueous sodium bicarbonate and dried over magnesium sulfate. After evaporation of the solvent, the acetylated glycolipid was purified by chromatography (hexane/ethyl acetate). The intermediate product was dissolved in 30-40 mL methanol and treated with a catalytic amount of sodium methoxide. After 30-60 min the catalyst was removed by treatment with amberlite IR 120 (H+) and the solvent was evaporated. Further purification of the anomer by chromatography on ion exchanging resin generally proofed to be unnecessary.
The synthetic route of 5333-42-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; UNIVERSITI MALAYA; PINTAS PTE LTD; WO2006/98699; (2006); A1;,
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