As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 96-35-5, name is Methyl 2-hydroxyacetate, molecular formula is C3H6O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. name: Methyl 2-hydroxyacetate
A certain amount of methacryloyl chloride (0.144 mol) dissolved in anhydrous DCM (60 mL) was added dropwise to methyl glycolate (at a temperature of ?0 C and an argon (Ar) atmosphere) 0.144 mol), TEA (0.288 mol), anhydrous DCM (100 mL), stir overnight, wash and purify, and obtain pure product by column chromatography.
With the rapid development of chemical substances, we look forward to future research findings about 96-35-5.
Reference:
Patent; Southwest University; Xu Zhigang; Shi Xiaoxiao; Ma Xiaoqian; Bai Shuang; Xue Peng; Kang Yuejun; (15 pag.)CN107596383; (2019); B;,
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