Adding a certain compound to certain chemical reactions, such as: 86770-74-3, 2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 86770-74-3, blongs to alcohols-buliding-blocks compound. Product Details of 86770-74-3
Example 4 This example describes two methods for the preparation of bis-N,N’-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl)perylenetetracarboxylic diimide. Method A: 2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethanol (2.6 g, 13.5 mmol), perylenetetracarboxylic dianhydride (2.2 g, 5.6 mmol), and triethylamine (25 mL, 180 mmol) were mixed with 50 mL of dry DMSO (4A activated MS, 3 days) in a 250-mL flask under argon. After the reaction mixture was stirred for 4 h at 150 C., the reaction solution was cooled to 80 C. and transferred to a 1000-mL flask. A mixture of 600 mL 10% aqueous HCl and 300 mL methanol was added to the reaction solution, then the solution was stirred for additional 2 hours at 60 C. After the mixture was cooled to RT overnight, the precipitate was collected using paper filter. The resulting collection was washed with 400 mL water, and the water layer was re-extracted with 50 mL chloroform. The filtrate could be extracted with chloroform to gain more products, but these products were contaminated and needed column purification. The combined organic layer was concentrated to give the crude title product; further purification was carried out on a silica-gel column eluted with CH2Cl2/CH3OH (5:1). Detection of the products on TLC plates was accomplished using UV light or sulfuiric acid solution (5% conc. sulfuric acid in EtOH). The title compound was obtained as dark-red solid (3.6 g, 86% yield): Rf0.4 (CH2Cl2/CH3OH, 10:1). 1H-NMR (60-70 mg/0.5 ml; CDCl3/CD3OD/100/5) delta7.96 (d, 4H, J=8.1 Hz, aromatic ring), 7.61 (d, 4H, J=8.1 Hz, aromatic ring), 4.32 (t, 4H, J=5.7 Hz, CH2N), 3.65-3.29 (m, 28H, CH2OCH2, HOCH2); 13C-NMR (60-70 mg/0.5 ml; CDCl3/CD3OD/100/5) delta162.7, 133.1, 130.4, 128.1, 124.7, 122.5, 122.4, 72.9, 70.79, 70.76, 70.4, 70.2, 68.0, 61.6, 39.5. 1H-NMR (DMSO-d6) delta7.13 (bd, 4H, aromatic ring), 6.92 (bd, 4H, aromatic ring), 4.59 (t, 4H, J=5.7 Hz, CH2N), 3.65-3.29 (m, 28H, CH2OCH2, HOCH2); 13C-NMR (DMSO-d6) delta161.2, 131.4, 128.8, 125.9, 122.6, 120.2, 72.3, 69.8, 69.7, 69.6, 66.5, 60.2, 45.67. MS (MALDI): m/z 765.82 [M+Na]+. Anal. Calcd. for C40H42N2O12 (742.77): C, 64.68; H, 5.70; N, 3.77. Found: C, 64.24; H, 5.52; N, 3.83.
The synthetic route of 86770-74-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Washington State University Research Foundation; US7238792; (2007); B2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts