Adding a certain compound to certain chemical reactions, such as: 10160-24-4, 7-Bromo-1-heptanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C7H15BrO, blongs to alcohols-buliding-blocks compound. Computed Properties of C7H15BrO
2-(7-Bromoheptyloxy)tetrahydro-2H-pyran2 (3): Dihydropyran (5.20 g, 6.11 mmol) was added to a stirring 0C solution of 7-bromoheptane-l-ol (2) (1 1.0 g, 56.7 mmol) and a catalytic amount of PTSA in CH2C12. After stirring at rt for 12 h, the reaction mixture was diluted with CH2C12 (200 mL), washed with water (100 mL x 2), brine (100 mL chi 3), dried over anhydrous sodium sulphate, and evaporated. The residue was purified by silica gel column chromatography using a gradient of 10-20% ethyl acetate/hexane as eluent to give 2-(7- bromoheptyloxy)tetrahydro-2H-pyran (3) (14.50 g, 92%) as a colorless oil. TLC: 10% EtOAc/hexanes, Rf ~ 0.55; NMR (400 MHz, CDC13) delta 4.58-4.56 (m, 1H), 3.84-3.88 (m, 1H), 3.68-3.77 (m, 1H), 3.46-3.51 (m, 1H), 3.33-3.43 (m, 3H), 1.80-1.81 (m, 2H), 1.30-1.62 (m, 14 H).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,10160-24-4, 7-Bromo-1-heptanol, and friends who are interested can also refer to it.
Reference:
Patent; MCW RESEARCH FOUNDATION, INC.; IMIG, John, David; CAMPBELL, William, B.; FALCK, John, Russell; WO2012/138706; (2012); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts