Electric Literature of 627-18-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 627-18-9, name is 3-Bromopropan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: 3,4-Dihydropyran (DHP, 15 mmol) was added slowly to a stirred solution of bromohydrin (10 mmol) and p-toluenesulfonic acid (1 mmol) in dichloromethane (20 mL) on ice bath. After stirring at room temperature overnight, the reaction mixture was diluted with water and extracted with dichloromethane. The organic layer was washed with brine and dried over anhydrous Na2SO4. The solvent was evaporated under reduced pressure, and the residue was purified by flash column chromatography to afford 1-5 as a light yellow oil. 2-(3-Bromopropoxy)tetrahydro-2H-pyran (1). Yield 94.2%. 1H NMR spectrum, delta, ppm: 1.37-1.55 m (4H), 1.57-1.65 m (1H), 1.70-1.78 m (1H), 2.01-2.10 m (2H), 3.37-3.49 m (4H), 3.73-3.83 m (2H), 4.49-4.55 m (1H). 13C NMR spectrum, deltaC, ppm: 19.4, 25.4, 30.5, 30.6, 32.8, 62.1, 64.8, 98.7.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 627-18-9, 3-Bromopropan-1-ol.
Reference:
Article; Zhang; Dong; Meng; Huang; Li; Russian Journal of General Chemistry; vol. 88; 11; (2018); p. 2388 – 2393; Zh. Obshch. Khim.;,
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