Application of 106-28-5, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.106-28-5, name is (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-ol, molecular formula is C15H26O, molecular weight is 222.37, as common compound, the synthetic route is as follows.
To a stirred mixture of (E,E)-farnesol 1 (0.50 g, 2.25 mmol) in non-dried DCM (50 mL) under nitrogen was added Dess-Martin periodinane (1.43 g, 3.40 mmol), and the resulting mixture stirred for 2 h 50 min. Saturated aqueous sodium bicarbonate solution (20 mL) was added dropwise, the mixture stirred 10 min, then extracted with DCM (3 x 25 mL). The organic layer was dried (MgSO4), and the solvent was removed in vacuo. The crude product was purified using flash chromatography (19:1 hexanes: ethyl acetate) to give the title product (0.495 g, 99%) as a clear colourless oil.
Statistics shows that 106-28-5 is playing an increasingly important role. we look forward to future research findings about (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-ol.
Reference:
Article; Duhamel, Nina; Martin, Damian; Larcher, Roberto; Fedrizzi, Bruno; Barker, David; Tetrahedron Letters; vol. 57; 40; (2016); p. 4496 – 4499;,
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