In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 90369-75-8, name is (3-Chloro-2-methylphenyl)methanol, the common compound, a new synthetic route is introduced below. Application In Synthesis of (3-Chloro-2-methylphenyl)methanol
Diphenylphosphoryl azide (6.00 mL, 27.80 mmol) was added to a cooled (0 C.) solution of (3-chloro-2-methyl-phenyl)-methanol (3.66 g, 23.40 mmol) in ether. The resulting mixture was stirred for a few minutes and DBU (4.20 mL, 28.00 mmol) was added slowly. The reaction mixture was stirred for 14 hours, decanted into a clean flask and the residue was washed with more ether. The combined organic phases were concentrated to give the crude title azido compound. Spectroscopic data: 1H NMR (300 MHz, CDCl3.) delta 2.41 (s, 3H), 4.36 (s, 2H), 7.11-7.26 (m, 2H), 7.35 (dd, J=7.33 Hz, 1H).
The synthetic route of 90369-75-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Allerghan, Inc.; US2008/194650; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts