Reference of 68327-04-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.68327-04-8, name is (1S,2S)-2-Aminocyclopentanol hydrochloride, molecular formula is C5H12ClNO, molecular weight is 137.6079, as common compound, the synthetic route is as follows.
Boc2O (3.49 g, 15.98 mmol) was added to a solution, at 0C, of (1S,2S)-2- aminocyclopentan-1-ol-HC1 (2.0 g, 14.53 mmol) and Et3N (4.05 mL, 29.06 mmol) in methanol (20 mL) and stirred. The reaction was allowed to warm to room temperature and after overnight the reaction was concentrated and the crude was purified by column chromatography to give S 13 (2.87 g) as a white solid.
Statistics shows that 68327-04-8 is playing an increasingly important role. we look forward to future research findings about (1S,2S)-2-Aminocyclopentanol hydrochloride.
Reference:
Patent; REGENTS OF THE UNIVERSITY OF MICHIGAN; WANG, Shaomeng; AGUILAR, Angelo; ZHANG, Ke; XU, Shilin; XU, Tianfeng; BERNARD, Denzil; HUANG, Liyue; (285 pag.)WO2017/192543; (2017); A1;,
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