Application of 534-03-2, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 534-03-2, name is 2-Aminopropane-1,3-diol. A new synthetic method of this compound is introduced below.
The synthetic steps taken in this embodiment are as follows:Preparation of 5-dimethylamino-1,3-dioxan-2-one:After dissolving 19.97 g of serinol in 50 mL of formic acid, 40 mL of a 37% (w/v) formaldehyde solution was added, and the mixture was heated to 120 C for 8 hours, and then cooled to room temperature. After removing excess formic acid, formaldehyde and water from the product by a rotary evaporator, the product was evaporated to dryness with anhydrous magnesium sulfate. The filtrate was collected by filtration and subjected to distillation under reduced pressure. The fraction of 108-109 C was collected under a vacuum of 2 mbar, and crystallized at -20 C to obtain a pale intermediate in a yield of 63.6%. Characterization by infrared spectroscopy (FT-IR) and nuclear magnetic resonance spectroscopy (1H NMR) confirmed that the pale intermediate was 2-dimethylamino-1,3-propanediol.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,534-03-2, its application will become more common.
Reference:
Patent; Guangdong Microbiology Institute (Guangdong Microbiology Analysis To Detect Center); Dong Peng; Xie Xiaobao; Gan Shuzhao; Shi Qingshan; (8 pag.)CN109467547; (2019); A;,
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