Adding a certain compound to certain chemical reactions, such as: 3637-61-4, Cyclopentanemethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: Cyclopentanemethanol, blongs to alcohols-buliding-blocks compound. Recommanded Product: Cyclopentanemethanol
Methanesulfonyl chloride (13.8 mL, 178 mmol) was added drop wise and at 0 C. to a solution of cyclopentanemethanol (16.2 g, 162 mmol) in anhydrous pyridine (35 mL). The mixture was stirred at 0 C. for 5 h, poured into water (200 mL), and extracted with methylene chloride (3¡Á50 mL). The combined organic layers were washed with 1 M HCl (3¡Á20 mL) and brine (2¡Á20 mL), dried with anhydrous magnesium sulphate, and evaporated in vacuo. The residue was dissolved in anhydrous acetone (20 mL), and a solution of sodium iodide (24 g, 162 mmol) in acetone (50 mL) was added. The mixture was refluxed for 5 h. The formed precipitate was filtered off, and the filtrate was evaporated in vacuo. The residue was distilled and the fraction boiling at 71-75 C. (110 Torr) was collected to give iodomethylcyclopentane. Yield: 13.8 g (41%). 1H-NMR (CDCl3, delta ppm): 3.21 (d, J=6.9 Hz, 2H); 2.18 (hept, J=7.5 Hz, 1H); 1.95-1.45 (m, 6H); 1.35-1.11 (m, 2H).
The synthetic route of 3637-61-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Novo Nordisk A/S; US2008/139562; (2008); A1;,
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