As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 101597-25-5, name is 1,1-Bis(4-methoxyphenyl)prop-2-yn-1-ol, molecular formula is C17H16O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. category: alcohols-buliding-blocks
1.00 g (2.0 mmol) of the naphthol compound (19) and the following propargyl alcohol compound 0.81 g (3.0 mmol) was dissolved in 50 ml of toluene, 0.02 g of camphorsulfonic acid was further added, and the mixture was stirred under heating reflux for 1 hour. After the reaction, the solvent was removed and purification by chromatography on silica gel gave 1.02 g of a white powdery product. The yield was 69%.
With the rapid development of chemical substances, we look forward to future research findings about 101597-25-5.
Reference:
Patent; Tokuyama Corporation; Izumi, Shinobu; Teranishi, Kazuhiro; Daikoku, Yusuke; Sando, Mitsuyoshi; (46 pag.)JP5721544; (2015); B2;,
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