The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 3-Hydroxy-2,2-dimethylpropanal
EXAMPLE 2Purification of HPA A complete mixture was prepared at 55C by adding 2505 parts of water into 835 parts of the crude HPA obtained in Reference Example 1. The mixture was gradually cooled from 55C to 32C over 5 h under stirring and then kept at 32C for one hour. The resultant crystals were separated by solid-liquid separation using a top-discharge centrifugal separator and then washed with water, to obtain HPA having a purity of 96.5% by weight in 60% recovery. The water content was 12% by weight and the remaining TEA content was 0.01% by weight. Synthesis of SPG from Purified HPA Into a solution of 95 parts of PE in 1200 parts of water, were added 5 parts of p-toluenesulfonic acid (PTSA) and 26 parts of SPG crystals obtained in Reference Example 2 as seed crystals (1.7% by weight of the total feed amount into the reaction system). Then, an aqueous solution of the purified HPA prepared by dissolving 160 parts of the purified HPA in 65 parts of water under heating at 80C was further added dropwise over 3.5 h. The SPG content X was 14.8% by weight. The pH of the reaction liquid at the initiation of reaction was 1.8, and the reaction temperature was 90C. After the dropwise addition, the reaction liquid was aged for 2 h while maintaining the temperature at 90C. The pH of the reaction production solution at the completion of reaction was 1.8. After the aging, the reaction product solution was separated into wet SPG and 1240 parts of reaction mother liquor by solid-liquid separation. The wet SPG was washed with 460 parts of water and then dried, to obtain 147 parts of SPG crystals. The yield of SPG was 56.8 mol% based on the charged PE, and the purity of SPG crystals was 99.9% by weight when analyzed by GC. The average particle size of SPG crystals was 23 um when measured on a water dispersion of SPG crystals by using a wet particle size distribution analyzer after exposing the water dispersion to ultrasonic wave for 10 min. The amount of waste water (reaction mother liquor + recovered washings + recovered water in drying) was 1780 parts. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 37% by weight. First Recycling Reaction Next, a first recycling reaction was performed in the same manner as in the above synthesis except for making 1200 parts of the reaction mother liquor (85% by weight of the whole amount) and 95 parts of PE into a solution under heating and using 0.7 part of PTSA and 240 parts of the aqueous solution of the purified HPA. The yield of dried SPG was 96.5 mol% and the purity was 99.8% by weight. The average particle size after exposed to ultrasonic wave was 22 um. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 37% by weight. Second Recycling Reaction Next, a second recycling reaction was performed in the same manner as in the first recycling reaction except for using 1100 parts of the reaction mother liquor (83% by weight of the whole amount) and 100 parts of water. The yield of dried SPG was 94.6 mol% and the purity was 99.8% by weight. The average particle size after exposed to ultrasonic wave was 22 um. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 37% by weight. Third and Subsequent Recycling Reactions The above procedure was repeated to perform the recycling reactions up to 10 cycles. The yield of SPG was 94.0 mol%, the purity was 99.7% by weight, and the particle size after exposed to ultrasonic wave was 20 um or more, each in average of third to tenth recycling reactions. The amount of waste water was 584 parts in average. During the solid-liquid separation by filtration through a glass filter under reduced pressure, no crack occurred on the cake. The liquid content of SPG cake immediately after the filtration was 42% by weight in average.
With the rapid development of chemical substances, we look forward to future research findings about 597-31-9.
Reference:
Patent; MITSUBISHI GAS CHEMICAL COMPANY, INC.; EP1598357; (2005); A1;,
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