Analyzing the synthesis route of 5456-63-3

With the rapid development of chemical substances, we look forward to future research findings about 5456-63-3.

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5456-63-3, name is trans-2-Aminocyclohexanol hydrochloride. This compound has unique chemical properties. The synthetic route is as follows. category: alcohols-buliding-blocks

(0746) A solution of 6-(2′-hexyldecanoyloxy)hexan-l-al (2.4 g) and trans-2- aminocyclohexanol hydrochloride (0.35 g) in methylene chloride (10 (0747) mL)/tetrahydrofuran (10 mL) was treated with sodium triacetoxyborohydride (1.3 g) for 1.5 hours. The solution was washed with aqueous sodium hydrogen carbonate solution. The organic phase was dried over anhydrous magnesium sulfate, filtered and the solvent removed. The residue was passed down a silica gel column using a (0748) methanol/methylene chloride (0-8/100-92%)) gradient, yielding compound III-9 as colorless oil (0.6 g

With the rapid development of chemical substances, we look forward to future research findings about 5456-63-3.

Reference:
Patent; ACUITAS THERAPEUTICS, INC.; LIN, Paulo, Jia Ching; TAM, Ying; (211 pag.)WO2018/191719; (2018); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts