Synthetic Route of 355-80-6, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 355-80-6 as follows.
Add trichlorochlorazine (3.68g, 0.02mol) and 40mL of anhydrous dichloromethane to 250mLIn a three-necked flask, stir well under N2 protection at 0-5 C.Add sodium hydroxide (3.2 g, 0.08 mol) to the reaction flask and continue stirring.(2) octafluoropentanol(7mL, 0.05mol) with dichloromethane (20mL)After dilution, it was slowly added dropwise to a three-necked flask and reacted at 0-5 C for 2 hours.The temperature was then slowly raised to reflux, and the reaction was stopped for 4 h.(3) repeatedly washing the reaction solution with deionized water, 5% HCl solution, and deionized water in sequence,Until neutral. Rotary evaporation to remove CH2Cl2 and excess octafluoropentanol,This gave a fluorine-containing coupling agent 2-chloro-4,6-bis (octafluoropentyloxy) -1,3,5-triazine.Fluorinated coupling agentNMR and carbon spectra of 2-chloro-4,6-bis (octafluoropentyloxy) -1,3,5-triazine are shown in Figures 1 and 2.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,355-80-6, its application will become more common.
Reference:
Patent; Sichuan Qing Chemical University; Li Yanli; Wang Qinqin; Chen Liyi; Zou Wei; Song Yilan; Yang Hu; Yan Jie; (10 pag.)CN110437066; (2019); A;,
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