Electric Literature of 112-27-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 112-27-6, name is 2,2′-(Ethane-1,2-diylbis(oxy))diethanol. This compound has unique chemical properties. The synthetic route is as follows.
Phosphorus tribromide (0.47 mL, 5 mmol) was added dropwise to triethylene glycol (5) (3.0 g,20.0 mmol) at -10 C. Then, the reaction was stirred at room temperature for 4 h. After the completionof the reaction, H2O was added, and the pH was adjusted to 7 using 5 M NaOH, extracted with CH2Cl2and dried over anhydrous Na2SO4. Removal of the solvent under vacuum, followed by flash columnchromatography (2% MeOH/CH2Cl2) afforded 11 as yellow oil (1.57 g, 7.36 mmol, 49%)3; 1H NMR(400 MHz, CDCl3) delta 3.83 (t, J = 6.2 Hz, 1H), 3.76 – 3.72 (m, 1H), 3.69 (s, 2H), 3.64 – 3.60 (m, 1H),3.49 (t, J = 6.2 Hz, 1H); 13C NMR (100 MHz, CDCl3) delta 72.6, 71.2, 70.6, 70.4, 61.8, 30.3. The 1H and 13C spectroscopic data are in good agreement with those previously reported.
According to the analysis of related databases, 112-27-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Thanaussavadate, Bongkotrat; Ngiwsara, Lukana; Lirdprapamongkol, Kriengsak; Svasti, Jisnuson; Chuawong, Pitak; Bioorganic and Medicinal Chemistry Letters; vol. 30; 1; (2020);,
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