Application of 3068-00-6, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 3068-00-6, name is 1,2,4-Butanetriol. A new synthetic method of this compound is introduced below.
To neat butane- 1 ,2,4-triol (300 g, 2.83 mol) was added 4- methylbenzenesulfonic acid (10 g, 58 mmol). The reaction mixture was heated to 180C. After 2 hours, the reaction mixture was cooled to ambient temperature and tetrahydrofuran-3-ol was afforded by distillation of the mixture under reduced pressure (10 mm Hg; the product fraction was collected at 46C).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,3068-00-6, its application will become more common.
Reference:
Patent; MERCK SHARP & DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank; WO2013/52394; (2013); A1;,
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