Electric Literature of 1454-85-9, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1454-85-9, name is Heptadecan-1-ol. A new synthetic method of this compound is introduced below.
General procedure: Alcohol (1.0 eq.) and sodium hydride (60percent in mineral oil, 2.8 eq.) were introduced in dimethoxyethane (10 mL). The solution was refluxed up to the end of H2 emission. Then, a solution of (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate (1.4 eq.) in ethane-1,2-diol was added and the mixture was refluxed for 48 h. After cooling to room temperature, the solution was poured into water. The organic layer was extracted with diethyl ether and dried over Na2SO4. The solvents were removed under vacuum and the desired product was obtained after a purification by flash chromatography in chloroform. The advancement of the purification was followed by TLC in chloroform/acetone (90:10).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1454-85-9, its application will become more common.
Reference:
Article; Pinault, Michelle; Guimaraes, Cyrille; Couthon, Helene; Thibonnet, Jerome; Fontaine, Delphine; Chantome, Aurelie; Chevalier, Stephan; Besson, Pierre; Jaffres, Paul-Alain; Vandier, Christophe; Marine Drugs; vol. 16; 4; (2018);,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts