In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 33524-31-1, name is (2,5-Dimethoxyphenyl)methanol, the common compound, a new synthetic route is introduced below. Computed Properties of C9H12O3
EXAMPLE 1 Preparation of 2,5-dimethoxybenzyl bromide: 2,5-Dimethoxybenzyl bromide was prepared by a modified method described by A. L. Shulgin and E. M. Gal in J. Chem. Soc. (London), 1316 (1953). A solution of 4.35 ml (46.3 mmol) PBr3 in 60 ml CCl4 was added dropwise over a period of 1 hour while cooling with ice to a solution of 20 ml (138.9 mmol) 2,5-dimethoxybenzyl alcohol in 200 ml dry CCl4 and the resulting mixture stirred for 15 h at 20 C. in the absence of moisture. After decantation of the CCl4 phase and washing of the inorganic phase (phosphorous acid) with CCl4, the combined organic phases were chromatographed on neutral aluminium oxide (Alumina Woelm N-Super I) and concentrated. The crude product was purified by sublimation in a high vacuum (T=80-100 C.; 0.1 mbar); white needles (melting point 74.5 C., as measured with a Perkin Elmer DSC 7) (lit. 75-76 C.). Yield 20.2 g=45% of the theoretical.
The synthetic route of 33524-31-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Bayer Aktiengesellschaft; US4859731; (1989); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts