1074-16-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1074-16-4, name is 2-(2-Bromophenyl)ethanol, the common compound, a new synthetic route is introduced below.
A solution of 2-bromophenethylalcohol (10 g, 50 mmol) in thionyl chloride (45 ml_) was treated with dimethylformamide (0.1 ml_) and heated to reflux for 6 hours. The reaction mixture was cooled to 00C, quenched by the addition of H2O (100 ml_), extracted with ethyl ether (250 ml_), dried (Na2SO4), and evaporated to provide 2- bromophenethylchloride (9.0 g, 82%) as a yellow oil:HPLC purity 99.2% at 210-370 nm, 10.4 minutes; Xterra RP18, 3.5u, 150 x 4.6 mm column, 1.2 mL/minutes, 85/15-5/95 (ammonium formate buffer pH = 3.5/ACN+MeOH) for 10 minutes, hold 4 minutes.
Statistics shows that 1074-16-4 is playing an increasingly important role. we look forward to future research findings about 2-(2-Bromophenyl)ethanol.
Reference:
Patent; WYETH; WO2008/73956; (2008); A2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts